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Some Items of Interest to Process Chemists and Engineers  Organic

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griseofulvin is an orally administered antibiotic that provides effective treatment for most dermatophyte fungal infections. absorption of griseofulvin from the gastrointestinal tract is less than ideal, but it can be enhanced when ...The present investigation aimed at formulation, and performance evaluation of vesicular drug carrier system proniosomal gel for transdermal delivery of antifungal agent, griseofulvin. ... showed enhanced in vitro skin permeation flux of 3.682±0.186 µg/cm2/hr as compared to 0.028 ± 0.02 µg/cm2/hr for plain drug solution in water. Results indicated that the optimized PNG formulation of griseofulvin had better skin permeation potential than plain drug solution in water. ...
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